FEV1/FEC正常值下限可评估肺癌患者胸腔术后存活情形 人氣: 2242
Warning: date(): It is not safe to rely on the system's timezone settings. You are *required* to use the date.timezone setting or the date_default_timezone_set() function. In case you used any of those methods and you are still getting this warning, you most likely misspelled the timezone identifier. We selected the timezone 'UTC' for now, but please set date.timezone to select your timezone. in /home/globalmed/public_html/news_cn_view.php on line 64
2016-06-13
慢性阻塞性肺病及肺癌患者都有逐年增加的趋势,而吸烟与这两种疾病有着密不可分的关系。目前FEV1∕FEC数值0.7是普遍用于诊断COPD与否的标准,然而对于进行过胸腔手术的肺癌患者而言,此数值无法确实反映COPD与整体存活间关系,因此发表于《Respiratory Investigation》的最新研究认为以肺量计评估此患者的呼吸道阻塞状况需做调整。试验中,699位进行胸腔手术的肺癌病患接受肺量计评估,纪录其肺功能变数、肺癌组织型态及相关合并症,并将患者分为低于及高于FEV1∕FEC正常值下限( Lower limit of normal, LLN)两组。试验结果显示,曾吸烟的男性低于LLN比例明显偏高,而低于LLN者其IC∕TLC (Inspiratory capacity/Total lung capacity)、DLCO (Diffusion capacity of the lung for carbon monoxide)、无病存活期及整体存活数值也明显较差,因此研究人员认为FEV1∕FEC的LLN对于整体存活的判断,优于以固定数值0.7的判断方式。
研究刊登在《Respiratory Investigation》的网页
http://www.respiratoryinvestigation.com/article/S2212-5345(15)00160-4/abstract
研究刊登在《Respiratory Investigation》的网页
http://www.respiratoryinvestigation.com/article/S2212-5345(15)00160-4/abstract